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S-PLEX assay development and sample-testing services are available to clients who need even more sensitivity than is currently available from other MSD assays. Now you can detect and quantify very low abundance proteins in your samples with the confidence that you are specifically measuring your protein of interest. S-PLEX: TrueSensitivity, Simple Execution S-PLEX is MSD’s ultra-sensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. Detection limits in the low femtogram/mL range are common.

According to an announcement published on Plex’s Web site on February 5, 2020 Plex Media Server instances which have either been deployed on a public-facing network DMZ or in an Internet Data Center (IDC), or with manually configured port-forwarding rules which forward specific UDP ports from the public Internet to devices running Plex Media.
The Plex Solution offers a tool(s) or display functionality that is available to you via your mobile phone or other mobile computing device (“Mobile Plex Solution(s)”). Please note that your mobile carrier’s normal messaging, data, and other rates and fees will apply to your use of the Mobile Plex Solution(s).

Media centers are the perfect place to store collections of images, music, and videos that people create on their computers, smartphones, or other devices. Their primary function is to store this media, such as your latest vacation photos or your favorite film. However, you may find your patience being tested if you start searching for a particular file, only to realize that nothing is organized properly.

If you’re looking for a suitable management platform for your media files, you will no doubt come across Plex eventually. Launched as a freeware project in 2007, Plex has an impressive range of features and is undoubtedly one of the best media centers of all time. Thanks to various streaming portals and services like Netflix, YouTube, Hulu, or Vevo, Plex users can play online content directly through their media center interface. However, Plex does have some formidable alternatives.

What should a good alternative to Plex be able to do?

The primary function of a media center is to organize all media files (audio, video, and image) on the selected computer system in a clearly arranged format. The user interface should make it easy for you to find and play back the content you want.

Plex alternatives (as well as Plex itself) should not just allow playback on the original device, but should also be able to play through external devices. Streaming your own media content on a TV should be a standard feature, which is why most media center interfaces are also designed to be used with smart TVs.

The best Plex alternatives should also be able to stream video and information services. Of course, your personal interests are most important here: Netflix and YouTube are more widely supported than other services because of their popularity. However, if you are not interested in these mainstream platforms, streaming links will be irrelevant to you as a user. It is therefore advisable to check the additional features in advance (often available as optional add-ons) that can be used as a respectable alternative to Plex. It is also important that the selected media management option allows multiple devices to access the library at the same time. If you want to enjoy a film while a roommate or a family member is streaming music, your chosen Plex alternative must always be usable by several people at the same time.

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What are the best alternatives to Plex?

In addition to the range of functions, cost and compatibility play an important role when it comes to choosing the best media center. The latter does not just deal with which systems the media center should be created on, it is also about what platforms you can access the media center from. You should also consider how up to date the Plex alternative is when making your decision: since many media centers are interconnected with web services, timely updates to close security holes are particularly important.

To make finding a suitable Plex alternative easier, here are some interesting examples of the best media centers and a guide to their advantages and disadvantages.

Mezzmo

On December 20th 2007, the Australian-based software company Conceiva released their home entertainment product Mezzmo. The software was initially available as a paid program for Windows, but Conceiva now relies on a freemium model: you can download and use the basic model for free, while the pro edition (which includes a web interface so that you can access using standard browsers) has lots of extra features and requires a subscription fee. There is also a paid Android app which was released in 2014. The app is mainly used as a remote application to retrieve content stored on the local Mezzmo media server on Android devices. Thanks to an integrated digital media server (DMS), you can also stream files stored on the device itself with the app.

Mezzmo is very easy to set up: after installing the program, it automatically searches and organizes all the movies, video clips, music, photos, and stored subtitles saved on the system being used. These files can subsequently be played back on all devices in the network that support UPnP or DNLA, or that have the app installed (Android only) – Mezzmo transcodes the media content in real time to ensure optimal streaming quality. You can access the media collection simultaneously with multiple devices at any time, so that sharing the media center is no problem. If you are having technical problems with Mezzmo, you can contact Conceiva with a ticket or through the user forum.

Advantages	Disadvantages
Multi-user capability	Media center cannot be used on macOS/Linux systems
Android app with its own media server	Web interface is only available in the paid pro edition

MediaPortal

In February 2014, Erwin Becker launched the GPL-licensed open source programMediaPortal, which is now managed by the MediaPortal team. A core feature of MediaPortal is that it supports TV cards so that you can watch TV through your media center. Additionally, the free-of-charge Plex alternative combines FM and internet radio with TV stations, information services (weather, news, etc.), and all media files stored on the computer in a single user interface. It’s up to you to decide how content should be categorized: you can sort songs by artist, album, or genre, and video clips and movies by cover, actor, or genre.

MediaPortal is an open source application and therefore benefits enormously from collaborating with the community: plugins developed as a supplement that provide additional functions that can be installed and integrated just as easily as skins to give the user interface a new appearance. This Plex alternative is only available for Windows and there are no separate apps for smartphones, tablets, or smart TVs – but there are extensions that allow remote access to your MediaPortal library from these same devices. All skins and plugins are available at any time from the official download page.